Brown adipose tissue thermogenesis in neonatal and cold-adapted animals.

نویسندگان

  • B Cannon
  • J Nedergaard
چکیده

25 1-268 Seydoux, J., Trimble, E. R., Bouillaud, F., Assimacopoulos-Jeannet, F., Bas, S., Ricquier, D., Giacobino, J. P. & Girardier, L. (1984) FEBS Lett. 166, 141-145 Shibata, H. & Nagasaka, T. (1984) Jap. J. Physiol. 34, 103-1 11 Sundin, ‘U. & Fain, J. N. (1983) Biochem. Pharmacol. 32, 3117-3120 Sundin, U., Mills, I. & Fain, J. N. (1984) Metabolism 33, 1028-1033 Szillat, D. & Bukowiecki, L. J. (1983) Am. J. Physiol. 245, E55SE559 Thureson-Klein, O., Lagercrantz, H. & Barnard, T. (1976) Acta Physiol.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Brown fat is essential for cold-induced thermogenesis but not for obesity resistance in aP2-Ucp mice.

The role of brown adipose tissue in total energy balance and cold-induced thermogenesis was studied. Mice expressing mitochondrial uncoupling protein 1 (UCP-1) from the fat-specific aP2 gene promoter (heterozygous and homozygous aP2-Ucp transgenic mice) and their nontransgenic C57BL6/J littermates were used. The transgenic animals are resistant to obesity induced by a high-fat diet, presumably ...

متن کامل

Brown adipose tissue: function and physiological significance.

The function of brown adipose tissue is to transfer energy from food into heat; physiologically, both the heat produced and the resulting decrease in metabolic efficiency can be of significance. Both the acute activity of the tissue, i.e., the heat production, and the recruitment process in the tissue (that results in a higher thermogenic capacity) are under the control of norepinephrine releas...

متن کامل

Reduced rearing temperature augments responses in sympathetic outflow to brown adipose tissue.

Sympathetic outflow to brown adipose tissue (BAT) contributes to both thermoregulation and energy expenditure in rats through regulation of BAT thermogenesis. Acute cold exposure in mature animals augments BAT thermogenesis; however, the enhanced BAT thermogenic response returns to normal shortly after cessation of the cold exposure. In this study, we sought to determine whether cold exposure i...

متن کامل

Lasting consistency of cold adaptability in rats reared in cold for many generations.

Wistar rats were successively reared in cold at 5 degrees C from 1969 to 1984. The historical changes observed in these rats were reported. The cold-adapted rats reared in cold for 8 to 11 successive generations (C8-11G) were examined on their cold tolerance and non-shivering thermogenesis. C8-11G rats showed greater nonshivering thermogenesis than that of the warm-adapted control group (W), an...

متن کامل

Cold adaptation overrides developmental regulation of sarcolipin expression in mice skeletal muscle: SOS for muscle-based thermogenesis?

Neonatal mice have a greater thermogenic need than adult mice and may require additional means of heat production, other than the established mechanism of brown adipose tissue (BAT). We and others recently discovered a novel mediator of skeletal muscle-based thermogenesis called sarcolipin (SLN) that acts by uncoupling sarcoendoplasmic reticulum Ca(2+)-ATPase (SERCA). In addition, we have shown...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Biochemical Society transactions

دوره 14 2  شماره 

صفحات  -

تاریخ انتشار 1986